Real-world Impact of Flaring on Patient-Reported Outcomes and Healthcare Resource Utilisation in Systemic Lupus Erythematosus

Clin Exp Rheumatol. 2021.Epub ahead of print

Data from the real world underscores the need for more effective strategies and treatments to alleviate or prevent flaring in systemic lupus erythematosus (SLE).

Despite data from Hong Kong and Canada showing an association of flaring with reduced health-related quality of life and increased healthcare resourse utilisation and costs, similar international data are limited.

Costenbader, et al. investigated the association of flaring with patient-reported outcomes, healthcare resource utilisation and income, in patients with SLE in Europe and the USA. They found that worse patient-reported outcomes and higher healthcare resource utilisation were associated with flaring in SLE.


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