Trial of Anti-BDCA2 Antibody Litifilimab for Cutaneous Lupus Erythematosus

N Engl J Med. 2022;387(4):321–331 doi: 10.1056/NEJMoa2118024

Werth, et al. investigate the efficacy and safety of litifilimab, a humanised IgG1 monoclonal antibody against blood dendritic cell antigen 2 (BDCA2), in patients with moderate-to-severe subacute and chronic cutaneous lupus erythematosus, with or without systemic manifestations, with results showing superiority to placebo.


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